Associate Professor of Biological Sciences
Location:3933 Wood Hall, Mail Stop 5410
Mailing address:Department of Biological Sciences
Western Michigan University
1903 W Michigan Ave
Kalamazoo MI 49008-5410 USA
- Molecular biology
Dr. John Geiser is an associate professor in the Department of Biological Sciences at Western Michigan University.
Geiser has two ongoing laboratory projects each using molecular biology and fungal genetics to reach the desired goal.
- Generation of novel drugs through engineering of cyclic peptide producing organisms. The goal is to engineer fungal strains capable of expressing novel cyclic peptides with anti-biotic or anti-fungal properties. This collaborative project with AureoGen Biosciences, Inc. uses genetics, molecular biology and biochemical techniques in multiple fungal systems.
- Identification of cellular targets of Yersinia pestis (plague). The goal is to understand the structure/function relationship of protein toxins of Yersinia pestis responsible for inactivation of immune cells during infection and subsequent establishment of plague. Geiser uses a yeast model system to identify cellular targets of YopO, YopT and YopE using the two-hybrid system and characterization of dominant suppressors. This work is pursued using genetics, molecular biology and biochemical techniques in the yeast Saccharomyces cerevisiae.